Using the knowledge you gained from the readings, evaluate how a typical drug, when orally administered, may be handled differently by these two patients:

• Ms. Jones is a 30-year-old female personal trainer that is 5 4 tall weighing 110lbs. She regularly drinks socially and sometimes more than a bit when she meets with her bi-weekly book club.
• Mr. Smith is a 65-year-old software tester who is 6 tall and weighs 235lbs. He drinks only occasionally.

Assume no other significant medical history or issues with either patient. In your analysis, compare how the two patients will metabolize the drug considering weight, gender, distribution of body water and body fat, age, metabolic state, and alcohol use. Explain how these factors impact the pharmacokinetics of the drug (half-life, dosage, route of administration, and elimination of the drug). Evaluate the impact on the risk-benefits analysis of the use of this drug.

Imagine that you are presenting to a group of people about the Psychosocial developmental domain. The resource you create will inform and educate a designated audience about the risk and protective factors of the research question you have chosen and most importantly, highlight evidence-based strategies that support positive outcomes for the psychosocial developmental domain highlighted this week among a chosen poque of childhood. Remember you are not restating the content form the 5-step design worksheet in your educational resource, you are using the worksheet to guide your development of the educational resource. The educational resource you create will be a powerpoint, Prezi, infographic or a pamphlet. Please review the signature assignment for more detailed instructions.

Locate a current Request for Proposal (RFP) or grant solicitation for a public safety issue. Write a brief summary of the grant (title, organization, purpose) and describe the requirements for a proposal. Which part(s) will be the most difficult to satisfy and why?